In medicine, the development of the body over the course of puberty is broken down into five stages, called Tanner Stages.

Blocker medications such as GNRH Agonists are usually not available until the onset of puberty at Tanner Stage 2. This generally involves the following changes:

In those assigned female at birth

  • Usually starts around age 11
  • Breast buds develop
  • Areolae begin to swell
  • Pubic hair starts to develop
  • Start to grow taller

In those assigned male at birth

  • Usually starts around age 12
  • Scrotum thins, testicles increase in size
  • Pubic hair starts to develop

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